PD-1/PD-L1-IN-14

• Catalog Number: orb1688110
• Category: Small Molecules
• Description: PD-1/PD-L1-IN-14
• CAS Number: 2499965-12-5
• MW: 400.47
• SMILES: OCCNCC=1C=CC=C(C1)NC2=NN=C(O2)C=3C=CC=C(C=4C=CC=CC4)C3C
• Formula: C₂₄H₂₄N₄O₂
• Biological Activity: PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM). By inhibiting the interaction of PD-1/PD-L1, PD-1/PD-L1-IN-14 promotes dimerization, endocytosis and degradation of PD-L1.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.