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Catalog Number | orb1305719 |
---|---|
Category | Small Molecules |
Description | PD-161570 |
CAS Number | 192705-80-9 |
Purity | 99.23% |
MW | 532.51 |
SMILES | N(C(NC(C)(C)C)=O)C=1C(=CC2=C(N1)N=C(NCCCCN(CC)CC)N=C2)C3=C(Cl)C=CC=C3Cl |
Formula | C26H35Cl2N7O |
Biological Activity | PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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