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Catalog Number | orb1298477 |
---|---|
Category | Small Molecules |
Description | PD-089828 |
CAS Number | 179343-17-0 |
Purity | 96.78% |
MW | 405.28 |
SMILES | N(C(NC(C)(C)C)=O)C=1C(=CC2=C(N1)N=C(N)N=C2)C3=C(Cl)C=CC=C3Cl |
Formula | C18H18Cl2N6O |
Biological Activity | PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM) |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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