Pax2 inhibitor EG1

• Catalog Number: orb691999
• Category: Small Molecules
• Description: Pax2 inhibitor EG1 (EG1) is a potent, small molecule inhibitor of Pax2 mediated transcription activation, effectively blocks Pax2 activity and DNA binding with Kd of 1.35-1.5 uM; inhibits Pax2 mediated expression with IC50 of 10 uM, and inhibits proliferation of Pax2 positive renal and ovarian cancer cell lines but has little effect on Pax2 negative cancer cells; inhibits embryonic kidney development.
• CAS Number: [693241-54-2]
• MW: 390.38
• SMILES: C(C1C(NC(C2C=CC(NC(C3C(OC)=CC=CC=3)=O)=CC=2)=O)=CC=CC=1)(=O)O
• Formula: C₂₂H₁₈N₂O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.