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Catalog Number | orb66937 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal to PARP.Poly [ADP-ribose] polymerase 1 (PARP) is involved in the base excision repair (BER) pathway bycatalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatinarchitecture and in DNA metabolism. This modification follows DNA damages and appears as anobligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARPpositively regulates the transcription of MTUS1 and negatively regulates the transcription ofMTUS2/TIP150. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | N-terminal region of human PARP |
Dilution range | WB:1:1000-1:5000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 113 |
UniProt ID | P09874 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-PARP antibody,anti-ADPRT antibody,anti-PPOL a Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Jurkat using PARP antibody
WB | |
Hamster, Mouse, Rat | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |