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Catalog Number | orb1302131 |
---|---|
Category | Small Molecules |
Description | Pamiparib |
CAS Number | 1446261-44-4 |
Purity | 99.53% |
MW | 298.31 |
SMILES | C[C@@]12C3=C4C=5C(N3)=CC(F)=CC5C(=O)NN=C4CN1CCC2 |
Formula | C16H15FN4O |
Biological Activity | Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can be used for the research of various cancers including the solid tumor |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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