Pamiparib maleate

• Catalog Number: orb1699723
• Category: Small Molecules
• Description: Pamiparib maleate
• CAS Number: 2086689-94-1
• Purity: 98%
• MW: 944.859
• SMILES: OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
• Formula: C₄₄H₄₂F₂N₈O₁₄
• Biological Activity: Pamiparib is a highly potent and selective PARP inhibitor. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability, and eventually leads to apoptosis.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.