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Catalog Number | orb1685760 |
---|---|
Category | Small Molecules |
Description | Pacritinib hydrochloride |
CAS Number | 1228923-43-0 |
Purity | 98% |
Formula | C28H32N4O3.xClH |
Biological Activity | Pacritinib hydrochloride is a potent inhibitor of wild-type JAK2 (IC50: 23 nM) and the JAK2V617F mutant (IC50: 19 nM). Pacritinib hydrochloride can be used in the study of acute myeloid leukaemia (AML) and myelofibrosis (MF). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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