p57 Kip2 Antibody

• Catalog Number: orb1730859
• Category: Antibodies
• Description: p27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: IHC, IP, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human p57 Kip2
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 32 kDa; Observed MW: 57 kDa
• Entrez: 1028
• UniProt ID: P49918
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.