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Catalog Number | orb1729815 |
---|---|
Category | Antibodies |
Description | The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | FC, IHC, IP, WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | A synthetic peptide of human p21 |
Dilution range | IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100; RCM: 1/50-1/100 |
Conjugation | Unconjugated |
MW | Calculated MW: 18 kDa; Observed MW: 21 kDa |
Entrez | 1026 |
UniProt ID | P38936 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
FC, IHC-P, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
FC, ICC, IF, IHC, WB | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
IF, IHC, WB | |
Human, Mouse, Rabbit | |
Rabbit | |
Polyclonal | |
Unconjugated |
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