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Catalog Number | orb1307925 |
---|---|
Category | Small Molecules |
Description | OSMI-1 |
CAS Number | 1681056-61-0 |
Purity | 99.83% |
MW | 563.64 |
SMILES | [C@@H](C(N(CC1=CC=CO1)CC2=CC=CS2)=O)(NS(=O)(=O)C=3C=C4C(=CC3)NC(=O)C=C4)C5=C(OC)C=CC=C5 |
Formula | C28H25N3O6S2 |
Biological Activity | OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1681056-61-0 |
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