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Osimertinib
Catalog Number: orb1305406
| Catalog Number | orb1305406 |
|---|---|
| Category | Small Molecules |
| Description | Osimertinib |
| CAS Number | 1421373-65-0 |
| Purity | 99.83% |
| MW | 499.61 |
| SMILES | CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4)=NC=C3 |
| Formula | C28H33N7O2 |
| Biological Activity | Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Mereletinib (AZD-9291,Osimertinib) [orb180883]
[1421373-65-0]
499.61
C28H33N7O2
100 mg, 1 g, 250 mg, 1 ml x 10 mm (in DMSO) - Item 1 of 1
AZD-9291 mesylate (Osimertinib, Mereletinib) [orb320147]
[1421373-66-1]
595.72
C29H37N7O5S
1 g, 100 mg, 250 mg
