You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1300874 |
---|---|
Category | Small Molecules |
Description | OSI-027 |
CAS Number | 936890-98-1 |
Purity | 98% |
MW | 406.44 |
SMILES | NC=1C2=C(N=C(N2N=CN1)[C@H]3CC[C@H](C(O)=O)CC3)C=4NC=5C(C4)=CC=CC5OC |
Formula | C21H22N6O3 |
Biological Activity | OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
936890-98-1 |
Filter by Rating