Ono 1301

• Catalog Number: orb1699770
• Category: Small Molecules
• Description: Ono 1301
• CAS Number: 176391-41-6
• MW: 428.48
• SMILES: C(CO/N=C(\C1=CC=CC=C1)/C=2C=CC=NC2)C=3C=4C(=C(OCC(O)=O)C=CC4)CCC3
• Formula: C₂₆H₂₄N₂O₄
• Biological Activity: Ono 1301 is a prostaglandin I2 mimetic coumpound with inhibitory activity against thromboxane A2 synthase. Ono 1301 suppresses pancreatic fibrosis in the DBTC-induced CP model by inhibiting monocyte activity not only with induction of HGF but also by Ono 1301 itself. It also works through promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.