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Catalog Number | orb1304620 |
---|---|
Category | Small Molecules |
Description | Olaparib |
CAS Number | 763113-22-0 |
Purity | 99.90% |
MW | 434.46 |
SMILES | C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3 |
Formula | C24H23FN4O3 |
Biological Activity | Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 μM), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[763113-22-0] | |
434.46 | |
C24H23FN4O3 |