OGG1

• Catalog Number: orb1729590
• Category: Proteins
• Description: OGG1 is a DNA glycosylase enzyme which takes part in base excision repair. OGG1 protein is the main enzyme accountable for the excision of 7, 8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which arises as a result of exposure to reactive oxygen species (ROS). OGG1 shows beta lyase activity that nicks DNA 3'' to the lesion.
• Species/Host: E. coli
• Tested applications: SDS-PAGE
• Tag: Histidine
• Concentration: 1mg/mL
• Dilution range: NA
• Form/Appearance: Lyophilized
• Purity: ≥95%
• Conjugation: Unconjugated
• MW: ~40 kDa
• Hazard Information: For Research use only
• Solubility (25°C): Soluble in PBS at 25°C
• Protein Sequence: SSGLVPRGSHTGSMPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLRQCRHAQEPPAKRRKGSKGPEG
• Source: Human
• Expression System: Intercellular
• Biological Origin: Recombinant protein expressed as His tage protein in E.coli
• Endotoxins: Not tested
• Storage: After reconstitution, store at -20°C; Avoid repeated freeze thaw
• Buffer/Preservatives: No preservative
• Alternative names: HMMH, HOGG1, MUTM, OGH1
• Note: For research use only
• Application notes: For research use only
• Expiration Date: 6 months from date of receipt.