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Catalog Number | orb1307935 |
---|---|
Category | Small Molecules |
Description | Ogerin |
CAS Number | 1309198-71-7 |
Purity | 99.90% |
MW | 307.35 |
SMILES | C(O)C1=C(C=CC=C1)C=2N=C(NCC3=CC=CC=C3)N=C(N)N2 |
Formula | C17H17N5O |
Biological Activity | Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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