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Obatoclax
Catalog Number: orb1690036
| Catalog Number | orb1690036 |
|---|---|
| Category | Small Molecules |
| Description | Obatoclax |
| CAS Number | 803712-67-6 |
| Purity | 98% |
| MW | 317.38 |
| SMILES | C(=C1N=C(C=C1OC)C2=CC=3C(N2)=CC=CC3)C4=C(C)C=C(C)N4 |
| Formula | C20H19N3O |
| Biological Activity | Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Obatoclax [orb1223966]
> 98% (HPLC)
803712-79-0
5 mg, 1 g, 500 mg, 200 mg, 10 mg, 25 mg, 50 mg, 100 mg
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