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Catalog Number | orb1910713 |
---|---|
Category | Small Molecules |
Description | NVS-STG2 is a small molecule STING agonist with AC50 of 5.2 μM. NVS-STG2 induces the high-order oligomerization of human STING by binding to a pocket between the transmembrane domains of the neighboring STING dimers and elicit potent STING-mediated immune responses in cells and antitumor activities in animal models. |
MW | 427.53 |
SMILES | COC1=C(C=CC(C(O)=O)=C1)NCC2=CC=C(C=C2)C3(OCC(C)(CO3)C)C(C)(C)C |
Formula | C25H33NO5 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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