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Catalog Number | orb341702 |
---|---|
Category | Small Molecules |
Description | BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM. |
CAS Number | [1028385-32-1] |
MW | 641.73814 |
SMILES | CN(C1=C2C3=CC(C4=CC5=CC=CC=C5N=C4)=CC=C3N=C1)C(N2C6=CC=C(C=C6)C(C)(C#N)C)=O.CC7=CC=C(S(=O)(O)=O)C=C7 |
Formula | C30H23N5O.C7H8O3S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of NVP-BEZ235 Tosylate