NVP-2

• Catalog Number: orb1307939
• Category: Small Molecules
• Description: NVP-2
• CAS Number: 1263373-43-8
• Purity: 99.76%
• MW: 513.07
• SMILES: C(NC=1N=C(C=CC1)C=2C=C(N[C@H]3CC[C@H](N[C@@H](COC)C)CC3)N=CC2Cl)C4(C#N)CCOCC4
• Formula: C₂₇H₃₇ClN₆O₂
• Biological Activity: NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 μM, 0.706 μM, and 0.605 μM, respectively).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.