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Catalog Number | orb1819082 |
---|---|
Category | Small Molecules |
Description | Nurr1 agonist 2 |
CAS Number | 742058-34-0 |
Purity | 98.40% |
MW | 310.37 |
SMILES | C(O)(=O)C=1SC(=CC1)C2=CC=C(OCC3=CC=CC=C3)C=C2 |
Formula | C18H14O3S |
Biological Activity | Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand-binding domain (LBD) with a Kd of 0.14 μM. Nurr1 agonist 2 can be used to study parkinsonism. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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