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Catalog Number | orb783547 |
---|---|
Category | Small Molecules |
Description | NS8593 hydrochloride is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca2+-dependently (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), and does not affect the Ca2+-activated K+ channels of intermediate and large conductance (hIK and hBK channels, respectively). |
CAS Number | [875755-24-1] |
MW | 299.8 |
SMILES | [H]Cl.C1(N[C@@H]2CCCC3=C2C=CC=C3)=NC4=CC=CC=C4N1 |
Formula | C17H18ClN3 |
Hazard Information | Non-Toxic |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
875755-24-1 |
99.83% | |
875755-24-1 | |
299.8 | |
C17H18ClN3 |
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