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Catalog Number | orb1744674 |
---|---|
Category | Small Molecules |
Description | NR2F1 agonist 1 |
CAS Number | 374101-64-1 |
MW | 470.63 |
SMILES | CCSC1=NN=C2N1C1=C(C(=O)N2CCC2=CC=CC=C2)C2(CCCCC2)CC2=C1C=CC=C2 |
Formula | C28H30N4OS |
Biological Activity | NR2F1 agonist 1, a specific nuclear receptor NR2F1 activator, initiates dormancy programs in cancer cells by upregulating NR2F1 and its target genes controlling dormancy. This compound promotes neural crest-like features and suppresses growth in head and neck squamous cell carcinoma (HNSCC) through NR2F1 activation. Moreover, NR2F1 agonist 1 demonstrates tumor growth inhibition in a mouse primary tumor model. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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