Nonapeptide-1

• Catalog Number: orb1910621
• Category: Small Molecules
• Description: Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer.
• CAS Number: [158563-45-2]
• MW: 1206.503592
• SMILES: CC(C)[C@@H](C(N)=O)NC([C@H]1N(C([C@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CCCNC(N)=N)NC([C@@H](CC5=CC=CC=C5)NC([C@H]6N(C([C@H](CCSC)N)=O)CCC6)=O)=O)=O)=O)=O)=O)CCC1)=O
• Formula: C₆₁H₈₇N₁₅O₉S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.