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Catalog Number | orb1298655 |
---|---|
Category | Small Molecules |
Description | NNMTi |
CAS Number | 42464-96-0 |
Purity | 99.93% |
MW | 286.11 |
SMILES | [I-].NC1=CC=CC=2C1=CC=C[N+]2C |
Formula | C10H11IN2 |
Biological Activity | NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathway |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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