NMDAR/TRPM4-IN-2

• Catalog Number: orb2280004
• Category: Small Molecules
• Description: NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 shows neuroprotective activity. NMDAR/TRPM4-IN-2 prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. NMDAR/TRPM4-IN-2 protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.
• CAS Number: [2243506-33-2]
• MW: 293.631021
• SMILES: C(C1C=CC=C(Br)C=1)N(CC)CCN.Cl
• Formula: C₁₁H₁₈BRCLN₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.