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Catalog Number | orb2280004 |
---|---|
Category | Small Molecules |
Description | NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 shows neuroprotective activity. NMDAR/TRPM4-IN-2 prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. NMDAR/TRPM4-IN-2 protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss. |
CAS Number | [2243506-33-2] |
MW | 293.631021022797 |
SMILES | C(C1C=CC=C(Br)C=1)N(CC)CCN.Cl |
Formula | C11H18BRCLN2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.77% | |
2243506-33-2 | |
330.092 | |
C11H19BrCl2N2 |