NMDAR/TRPM4-IN-2

• Catalog Number: orb1744757
• Category: Small Molecules
• Description: NMDAR/TRPM4-IN-2
• CAS Number: 2243506-33-2
• Purity: 98.77%
• MW: 330.092
• SMILES: Cl.Cl.CCN(CCN)Cc1cccc(Br)c1
• Formula: C₁₁H₁₉BrCl₂N₂
• Biological Activity: NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprotective activity against NMDA-induced hippocampal neuronal cell death and mitochondrial dysfunction. NMDAR/TRPM4-IN-2 showed neuroprotective activity against NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons with an IC50 value of 2.1 μM.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.