NKIRAS1 Antibody

• Catalog Number: orb248144
• Category: Antibodies
• Description: NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: NRAS285
• Tested applications: WB
• Reactivity: Human, Mouse, Rat
• Isotype: Mouse IgG1, kappa
• Immunogen: A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
• Dilution range: Western blot: 5-10ug/ml
• Purity: Protein G purified antibody
• Conjugation: Unconjugated
• Formula: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This NKIRAS1 antibody is available for research use only.
• Entrez: 28512
• UniProt ID: Q9NYS0
• Storage: Aliquot the NKIRAS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Buffer/Preservatives: 1X PBS, pH 7.4
• Note: For research use only
• Application notes: Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.
• Expiration Date: 12 months from date of receipt.

Western blot testing of human samples with NKIRAS1 antibody at 6 ug/ml.