NKH477

• Catalog Number: orb1888128
• Category: Small Molecules
• Description: NKH477 (Colforsin dapropate hydrochloride) is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 exerts an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts.
• CAS Number: 138605-00-2
• MW: 546.09
• SMILES: O[C@@]12[C@@]3([C@@](C(C)(CC[C@@H]3O)C)([H])[C@H](OC(CCN(C)C)=O)[C@H](OC(C)=O)[C@]1(O[C@](C=C)(C)CC2=O)C)C.Cl
• Formula: C₂₇H₄₄ClNO₈
• Storage: Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles
• Alternative names: Colforsin dapropate hydrochloride, NKH-477, NKH 47
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

NKH477 Chemical Structure