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Nintedanib
Catalog Number: orb1307463
| Catalog Number | orb1307463 |
|---|---|
| Category | Small Molecules |
| Description | Nintedanib |
| CAS Number | 656247-17-5 |
| Purity | 99.85% |
| MW | 539.62 |
| SMILES | COC(c1cc2c(/C(C(N2)=O)=C(c3ccccc3)/Nc4ccc(N(C(CN5CCN(CC5)C)=O)C)cc4)cc1)=O |
| Formula | C62H64N10O8 |
| Biological Activity | Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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BIBF 1120 esylate [orb320236]
[656247-18-6]
649.76
C33H39N5O7S
1 ml x 10 mm (in DMSO), 100 mg, 1 g, 250 mg Nintedanib esylate hemihydrate [orb1741252]
0.98
959762-24-4
1317.54
C66H80N10O15S2
25 mg, 100 mg, 50 mg
