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Nepicastat
Catalog Number: orb1689394
| Catalog Number | orb1689394 |
|---|---|
| Category | Small Molecules |
| Description | Nepicastat |
| CAS Number | 173997-05-2 |
| Purity | 98% |
| MW | 295.35 |
| SMILES | C(N)C=1N([C@@H]2CC=3C(CC2)=C(F)C=C(F)C3)C(=S)NC1 |
| Formula | C14H15F2N3S |
| Biological Activity | Nepicastat (SYN117) is a selective, potent, and orally active dopamine-beta-hydroxylase inhibitor which can cross the blood-brain barrier (BBB). Nepicastat (SYN117) produces concentration-dependent inhibition of bovine and human dopamine-beta-hydroxylase with IC50s of 8.5 nM and 9 nM [1] [2] [3]. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
(R)-Nepicastat HCl [orb1686481]
98%
195881-94-8
331.81
C14H16ClF2N3S
1 mL*10mM (in DMSO), 100 mg, 50 mg, 25 mg, 10 mg, 5 mgNepicastat hydrochloride monohydrate [orb1739271]
0.98
177645-08-8
349.82
C14H18ClF2N3OS
25 mg, 100 mg, 50 mgNepicastat hydrochloride [orb1225959]
> 98% (HPLC)
170151-24-3
5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 g, 500 mg
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