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Catalog Number | orb1299831 |
---|---|
Category | Small Molecules |
Description | NDI-091143 |
CAS Number | 2375840-87-0 |
Purity | 98% |
MW | 453.84 |
SMILES | FC=1C(=CC(NS(=O)(=O)C2=CC(C(OC)=O)=CC(Cl)=C2O)=C(F)C1)C3=CC=CC=C3 |
Formula | C20H14ClF2NO5S |
Biological Activity | NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
2375840-87-0 |
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