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Catalog Number | orb1740278 |
---|---|
Category | Small Molecules |
Description | NBQX sodium |
CAS Number | 479347-86-9 |
Purity | 0.98 |
MW | 380.2415 |
SMILES | O=C1[N-]C2=C([N-]C1=O)C3=CC=CC(S(=O)(N)=O)=C3C([N+]([O-])=O)=C2.[Na+].[Na+] |
Formula | C12H6N4Na2O6S |
Biological Activity | NBQX, also known as FG9202, is an AMPA receptor antagonist. NBQX blocks AMPA receptors in micromolar concentrations (~10–20 µM) and also blocks kainate receptors. In experiments, it is used to counter glutamate excitotoxicity. NBQX was found to have anticonvulsant activity in rodent seizure models. As the disodium salt, NBQX is soluble in water at high concentrations (at least up to 100 mM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |