Naratriptan hydrochloride

• Catalog Number: orb1300624
• Category: Small Molecules
• Description: Naratriptan hydrochloride
• CAS Number: 143388-64-1
• Purity: 99.89%
• MW: 371.93
• SMILES: CNS(=O)(=O)CCc1cc2c(cc1)[nH]cc2C1CCN(CC1)C.Cl
• Formula: C₁₇H₂₆ClN₃O₂S
• Biological Activity: Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydrochloride) binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.