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nAChR agonist 1
Catalog Number: orb654563
| Catalog Number | orb654563 |
|---|---|
| Category | Small Molecules |
| Description | nAChR agonist 1 is a potent,?brain-permeable, and?orally?efficacious positive?allosteric?modulator?of α7?nicotinic?acetylcholine?receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 μM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease. |
| CAS Number | [1394371-75-5] |
| MW | 419.94 |
| SMILES | NS(=O)(=O)C1C=CC(C2C(C)=C(C3C=CC(Cl)=CC=3)SC=2C(=O)CC)=CC=1 |
| Formula | C20H18ClNO3S2 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
nAChR agonist 1 [orb1218861]
> 98% (HPLC)
1394371-75-5
200 mg, 100 mg, 1 g, 500 mg, 5 mg, 10 mg, 25 mg, 50 mgnAChR agonist 1 [orb1309361]
97.17%
1394371-75-5
419.94
C20H18ClNO3S2
25 mg, 10 mg, 5 mg, 1 mg, 100 mg, 50 mg, 1 mL*10mM (in DMSO)
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