N-Desethyl Sunitinib hydrochloride

• Catalog Number: orb1983191
• Category: Small Molecules
• Description: N-Desethyl Sunitinib hydrochloride
• MW: 406.88
• Formula: C₂₀H₂₄ClFN₄O₂
• Biological Activity: N-Desethyl Sunitinib (SU-12662) (hydrochloride), a metabolite of sunitinib, is a robust ATP-competitive inhibitor of VEGFR, PDGFRβ, and KIT, demonstrating inhibition constants (K i values) of 2, 9, 17, 8, and 4 nM for VEGFR-1, -2, -3, PDGFRβ, and KIT, respectively [1].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.