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Catalog Number | orb1689880 |
---|---|
Category | Small Molecules |
Description | MW-150 dihydrochloride dihydrate |
CAS Number | 1661020-92-3 |
Purity | 98% |
MW | 490.43 |
SMILES | O.O.Cl.Cl.CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 |
Formula | C24H29Cl2N5O2 |
Biological Activity | MW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active p38α MAPK inhibitor with a Ki of 101 nM. MW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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