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Catalog Number | orb82615 |
---|---|
Category | Proteins |
Description | Glia maturation factor beta(GMF beta) coded by GMFb gene at chromosome 14 in mouse, is identical to human GMF beta, with the exception of two amino acid residues. It is a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family, and plays an important role in the upstream regulation of excessive production and the releasing of proinflammatory cytokines/chemokines in brain cells, leading to the destruction of oligodendrocytes, the myelin forming cells, and neurons. Less than 1EU/μg of rMuGMF beta as determined by LAL method. |
Tested applications | FA, HPLC, SDS-PAGE |
Purity | > 97% pure by SDS-PAGE and HPLC analyses. |
Conjugation | Unconjugated |
MW | 16.4 kDa |
Target | GMF beta |
Protein Sequence | SESLVVCDVA EDLVEKLRKF RFRKETHNAA IIMKIDKDER LVVLDEELEG VSPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H |
Biological Origin | E.coli |
Biological Activity | Less than 1EU/μg of rMuGMF beta as determined by LAL method. |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Sterile Filtered White lyophilized (freeze-dried) powder. We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. |
Note | For research use only |
Application notes | Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions. |
Expiration Date | 6 months from date of receipt. |
> 97% by SDS-PAGE and HPLC analyses. | |
Approximately 16.4 KDa, a single non-glycosylated polypeptide chain containing 141 amino acid residues. | |
Escherichia coli. |