Murine FGF-18 protein

• Catalog Number: orb107720
• Category: Proteins
• Description: RecombinantMurine Fibroblast Growth Factor-18. Murine FGF-18 is encoded by the FGF18 gene. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles of in embryo development. FGF-18-/-mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF-18 has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. In addition, it also has significant roles in lung development and has an anabolic effect on cartilage formation.
• Tested applications: HPLC, SDS-PAGE
• Purity: > 95 % by SDS-PAGE and HPLC analyses
• Conjugation: Unconjugated
• MW: 21.0 kDa
• Target: FGF-18
• Protein Sequence: EENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLLVETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYSGWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQAELQK PFKYTTVTKRSRRIRPTHPG
• Biological Origin: E.coli
• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 m filtered concentrated solution in PBS, pH 7.4, 500 mM NaCl
• Alternative names: Murine Fibroblast Growth Factor-18 protein
• Note: For research use only
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Murine FGF-18 protein