MUC6 antibody

• Catalog Number: orb2276463
• Category: Antibodies
• Description: MUC6 antibody validated for immunohistochemistry on 76 different Normal Tissues
• Species/Host: Rabbit
• Clonality: Monoclonal
• Clone Number: Biorbyt-806R
• Tested applications: IHC
• Reactivity: Human
• Isotype: IgG
• Immunogen: Recombinant full-length human MUC6 protein
• Dilution range: 1:100-1:200
• Conjugation: Unconjugated
• UniProt ID: Q6W4X9
• Storage: Antibody with azide – store at 2 to 8°C. Antibody without azide – store at -20 to -80°C. Antibody is stable for 24 months. Non- hazardous. No MSD required.
• Alternative names: Gastric mucin 6; MUC6; MUC6 mucin; Mucin 6 oligome
• Note: For research use only
• Application notes: Positive Control: Stomach: Mucous secreting glands should be strongly positive. Negative Control: Stomach: Surface epithelium should be completely negative. Cellular Localization: Cytoplasmic Protocol Recommendations: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121°C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37°C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer’s directions.
• Expiration Date: 12 months from date of receipt.

Moderate to strong MUC6 positivity in the mucous secreting glands but not the surface epithelium – of the stomach.

Seminal vesicle epithelial cells exhibit high level MUC6 expression.

Strong and diffuse MUC6 immunostaining in a colorectal adenocarcinoma.