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Catalog Number | orb1909114 |
---|---|
Category | Small Molecules |
Description | MSA-2 dimer |
CAS Number | 2377881-92-8 |
MW | 568.66 |
SMILES | C(CCC1=C(OC)C=C2C(=C1)C=C(C(CCC(O)=O)=O)S2)C=3C=C4C(SC(C(CCC(O)=O)=O)=C4)=CC3OC |
Formula | C29H28O8S2 |
Biological Activity | MSA-2 dimer, a selective and orally active non-nucleotide STING agonist with a dissociation constant (Kd) of 145 μM, demonstrates prolonged antitumor and immunogenic activity. It non-covalently binds to STING as a dimer, showing greater permeability compared to cyclic dinucleotide[1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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