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MS4078
Catalog Number: orb611306
| Catalog Number | orb611306 |
|---|---|
| Category | Small Molecules |
| Description | MS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM). |
| CAS Number | [2229036-62-6] |
| MW | 914.47 |
| SMILES | CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O |
| Formula | C45H52ClN9O8S |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
MS4078 [orb1308005]
98.74%
2229036-62-6
914.47
C45H52ClN9O8S
1 mg, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mm (in DMSO)
