MS4078

• Catalog Number: orb611306
• Category: Small Molecules
• Description: MS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM).
• CAS Number: [2229036-62-6]
• MW: 914.47
• SMILES: CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O
• Formula: C₄₅H₅₂ClN₉O₈S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.