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Catalog Number | orb1308005 |
---|---|
Category | Small Molecules |
Description | MS4078 |
CAS Number | 2229036-62-6 |
Purity | 98.74% |
MW | 914.47 |
SMILES | O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCNC(CN4CCC(CC4)C5=CC(OC(C)C)=C(NC=6N=C(NC7=C(S(C(C)C)(=O)=O)C=CC=C7)C(Cl)=CN6)C=C5C)=O |
Formula | C45H52ClN9O8S |
Biological Activity | MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |