MS1943

• Catalog Number: orb654673
• Category: Small Molecules
• Description: MS1943 is a first-in-class, orally bioavailable EZH2 selective degrader, with an IC50 of 120 nM. MS1943 significantly reduces EZH2 protein levels in numerous triple-negative breast cancer (TNBC) and other cancer and noncancerous cell lines.
• CAS Number: [2225938-17-8]
• MW: 718.93
• SMILES: CC(C)N(N=C1)C2=C1C(C(NCC3=C(C)C=C(C)NC3=O)=O)=CC(C4=CC=C(N=C4)N(CC5)CCN5CCNC(CC67C[C@H]8C[C@H](C[C@H](C8)C7)C6)=O)=C2
• Formula: C₄₂H₅₄N₈O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.