MS-402

• Catalog Number: orb746418
• Category: Small Molecules
• Description: MS402 is a BD1-selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice.
• CAS Number: [1672684-68-2]
• MW: 370.83
• SMILES: O=C(NC1=CC=C(OC)C=C1)C2=CC=C(NC3=C(C)C(CC3)=O)C(Cl)=C2
• Formula: C₂₀H₁₉ClN₂O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.