MRTX849

• Catalog Number: orb654578
• Category: Small Molecules
• Description: MRTX849(Adagrasib) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. MRTX849 covalently binds to KRAS G12C at the cysteine at residue 12, locks the protein in its inactive GDP-bou
• CAS Number: [2326521-71-3]
• MW: 604.12
• SMILES: N#CC[C@@H]1N(C(C(F)=C)=O)CCN(C2=C3C(CN(C4=C5C(Cl)=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)C1
• Formula: C₃₂H₃₅ClFN₇O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.