MRTX849 acid

• Catalog Number: orb1690775
• Category: Small Molecules
• Description: MRTX849 acid
• CAS Number: 2561529-96-0
• Purity: 98%
• MW: 662.16
• SMILES: OC(=O)CCN1CCC[C@H]1COc1nc2CN(CCc2c(n1)N1CCN([C@@H](CC#N)C1)C(=O)C(F)=C)c1cccc2cccc(Cl)c12
• Formula: C₃₄H₃₇ClFN₇O₄
• Biological Activity: MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2 (HY-137516). LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC 50 s between 0.25 and 0.76 μM).
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.