MRTX1257

• Catalog Number: orb691940
• Category: Small Molecules
• Description: MRTX1257 (MRTX-1257, MRTX 1257) is a potent, selective, covalent and irreversible inhibitor of KRAS G12C, inhibits KRAS dependent ERK-phosphorylation in the H358 cell with IC50 of 0.9 nM.
• CAS Number: [2206736-04-9]
• MW: 565.722
• SMILES: C(#N)C[C@@H]1CN(C2N=C(OC[C@H]3CCCN3C)N=C3CN(C4=C5C(C=CC=C5C)=CC=C4)CCC3=2)CCN1C(=O)C=C
• Formula: C₃₃H₃₉N₇O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.