MRTX1133(MRTX-1133)

• Catalog Number: orb1089786
• Category: Small Molecules
• Description: MRTX 1133 is a potent and selective KRAS G12D inhibitor. MRTX1133 targets the KRAS G12D protein in both active and inactive states. In preclinical studies, MRTX1133 exhibited a long half-life, an ability to bind the KRAS G12D protein in both active and inactive states, and selective inhibition of KRAS G12D mutant cancer cells.
• CAS Number: [2621928-55-8]
• MW: 600.63
• SMILES: OC1=CC(C2=C(F)C3=NC(OC[C@@]45CCCN4C[C@H](F)C5)=NC(N6CC(N7)CCC7C6)=C3C=N2)=C8C(C#C)=C(F)C=CC8=C1
• Formula: C₃₃H₃₁F₃N₆O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.